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Primary hypothyroidism, caused by failure of the thyroid gland, is characterised by a decreased serum free thyroxine (FT4) level with an appropriately elevated serum thyroid stimulating hormone (TSH) level

Interpretation of the data is complicated by the fact that most of the studies are rather descriptive without exploring the underlying signaling cascades

Cons Bioavailability (absorption) of oral glutathione is questionable

Badger TM, Huang J, Ronis M, Lumpkin CK: Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high