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1998 Jun 16;97(23):2299-301

Nausea and acid reflux: SIBO can disrupt the normal functioning of the lower esophageal sphincter, leading to acid reflux and heartburn

Aflatoxin B 1 metabolism: regulation by phase I and II metabolizing enzymes and chemoprotective agents

That distinction is more important than most people realize because the Federal Food, Drug, and Cosmetic Act (FD&C Act) was designed to accomplish two important objectives