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A lack of folate, especially during early pregnancy, can prevent brain and spinal cord development and lead to nerve problems like numbness, tingling, and memory or mood changes

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However, a potential explanation of these findings might be sought in the observation that allergy, especially food allergy, and eosinophilic esophagitis are often reported in ASD patients (Figure 1)

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With the continued integration of interdisciplinary technologies and the acceleration of clinical translation, metabolic targeting in CRC is entering a new era of broad clinical applicability

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