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The loss of sulfite oxidase activity in ISOD and MocoD leads to severe neurological dysfunction characterized by cerebral atrophy, mental retardation, intractable seizures, and dislocation of ocular lenses

The Three Amino Acids Necessary for Higher Glutathione Concentrations The three amino acids that are critical for supporting higher glutathione concentrations and assisting with proper function include: Glutamate is the first in the peptide sequence, and its side chain interacts with the cysteine moiety in a somewhat unusual peptide linkage, known as the -glutamyl bond