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Limitation: No preservative, so microbial contamination risk increases over time

Although not inherently toxic, extended treatment with ASMswhich is common for patients suffering from a chronic disease like epilepsycan lead to the production and accumulation of toxic secondary metabolites inside the cells, leading to side effects like allergic reactions, cell death and organ damage in severe cases 6

This review aims to explore the nephroprotective role of botanicals, specifically focusing on the damage to kidneys caused by prolonged use of modern medicines and environmental toxicants

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