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While the number of particles in the second reconstruction was much lower than the first, the data were consistent with a lower number of particles in a CT-like conformation (~ 17% of particles) relative to the bypass conformation (55% of particles) compared to the percentage of particles previously observed for the Amy-CTR-Gs complex (note, in the repeat experiment 28% of the particles could not be confidently classified, due to poorly resolved in ECD features) (Supplementary Fig

Proposed Changes to the EHR Reporting Period for a Payment Adjustment Year for Eligible Hospitals In the definition of EHR reporting period for a payment adjustment year under 42 CFR 495.4, paragraphs (2)(vii) and (viii), we specify the EHR reporting periods in CYs 2023 and 2024 that apply for purposes of determining whether an eligible hospital may be subject to a downward payment adjustment in a later year, as follows: For CY 2023: (A) If an eligible hospital has not successfully demonstrated it is a meaningful EHR user in a prior year, the EHR reporting period is any continuous 90-day period within CY 2023 and applies for the FY 2024 and 2025 payment adjustment years

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We welcome any suggested revisions thereto and particularly seek comment on whether our proposed definition of PEC should include publicly-traded private equity companies