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MAD appears to be more encompassing and explanatory than the stand-alone A or Tau hypotheses as it bypasses the debate between them entirely (Kametani and Hasegawa, 2018), incorporating them as legitimate arms of a unified response

This mechanism plays a role in activating various downstream pathways, including RAS/MAPK, PI3K/AKT, Wnt/-catenin, and JAK/STAT, which are crucial for controlling a range of cellular physiological activities such as differentiation, proliferation, epithelial cell movement, angiogenesis, and EMT [21]

The tubes were kept in a cool rack throughout the extraction

Most compounded formulations also include glycine