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LY3437943 (Retatrutide): discovery to clinical proof of concept (triple GLP-1/GIP/glucagon agonist, preclinical mechanism) Nature Reviews Endocrinology (2024) Multi-receptor agonists for metabolic disease (mechanism of GLP-1/GIP/glucagon co-activation) Diabetes Care (2024) Incretin-based therapies: GLP-1, GIP, and glucagon receptor pharmacology (metabolic pathways, energy expenditure) NEJM (2023) Supplementary Material Jastreboff et al

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Therefore, future experimental models and human studies should explore in depth the specific mechanism of action of acupuncture on pathological changes in Tau and how this traditional medical technique can be effectively utilized to treat or prevent TBI-induced neurodegenerative diseases (Liu, 2023)