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* Chemical structures of neuroendocrine hormones (cortisol, testosterone, estradiol, and epinephrine), neurotransmitters (dopamine, norepinephrine, epinephrine, and its precursor tyrosine), and plant metabolites of adaptogenic plants tyrosol, salidroside, rosavin, eleutherosides, acteoside, schizandrins, ginsenoside Rg5, withanolide A, withaferin A, andrographolide, acteoside, 20-hydroxyecdysone, tanshinones, bacosides, bacoposodes, lancemasides, tangshenoside VIII codonoside B, salvianolic acids, p-coumaric, ferulic, synapic acids, and cucurbitacin R diglucoside

433 Rather than producing from mitochondrial TCA cycle under controlled conditions, the NADH in diabetic islets is generated by cytoplasmic sorbitol oxidation and mitochondrial pyruvate oxidation in response to diabetes and hyperglycemia stimulate