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Certain medications can also trigger an unexpected heat response

Advertisement However, these medications also have been implicated in a number of cutaneous adverse events, including infusion and injection site reactions, infection, inflammatory dermatoses and malignancy

Thus, a strict photoprotection with sunscreen as well as photo-protective clothing is advised

This selectivity occurs because AOD-9604 does not bind to growth hormone receptors in muscle tissue and works primarily through beta-3 adrenergic receptors that are predominantly expressed in fat cells