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In contrast, in the group treated with TPA alone, the mitochondrial membrane became denser, the mitochondrial cristae were incomplete, the cristae were fractured, and the mitochondrial matrix became darker in colour

[8] Compared with saline, delayed T4 did not shrink the lesion volume a telling detail, because it means the benefit was not simply less initial damage yet it significantly reduced hippocampal cell loss, enhanced angiogenesis and neurogenesis in the injured cortex and hippocampus, increased oligodendrogenesis, and improved sensorimotor recovery and spatial learning

[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Rosenberger D.C., Blechschmidt V., Timmerman H., Wolff A., Treede R.D

La entrega controlada de cobre a travs del complejo GHK-Cu evita la toxicidad del cobre libre mientras mantiene la biodisponibilidad para enzimas cobre-dependientes