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PMID: 40957950 NPJ Breast Cancer 2025 Jul 17;11(1):73

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However, the exact role of GST enzymes in the mechanism of ISR is still far from elucidated because transgenic plants overexpressing or suppressing the symbiont-inducible GSTs have been rarely studied (Kao et al., Conclusions and Future Perspectives Since the beginning of plant GST research in 1970 the fundamental questions have remained largely unanswered: what are the physiological roles of GST isoenzymes and which metabolites are the natural, endogenous substrates of GSTs

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