:
Wrinkle metrics were assessed by quantitative imaging at baseline and after the treatment period across matched skin regions
b) nonionic surfactants, which include for example, polyoxyethylene fatty alcohol esters, sorbitan fatty acid esters (Spans), polyoxyethylene sorbitan fatty acid esters (e.g., polyoxyethylene (20) sorbitan monooleate (Tween 80), polyoxyethylene (20) sorbitan monostearate (Tween 60), polyoxyethylene (20) sorbitan monolaurate (Tween 20) and other Tweens, sorbitan esters, glycerol esters, e.g., Myrj and glycerol triacetate (triacetin), polyethylene glycols, cetyl alcohol, cetostearyl alcohol, stearyl alcohol, polysorbate 80, poloxamers, poloxamines, polyoxyethylene castor oil derivatives (e.g., Cremophor RH40, Cremophor A25, Cremophor A20, Cremophor EL) and other Cremophors, sulfosuccinates, alkyl sulfates (SLS)
The choice between them for formulation purposes may depend on stability in specific vehicle systems, skin feel, and manufacturer preference rather than on demonstrated differences in biological efficacy
