10.1021/acsomega.9b00205
This could represent a significant advantage for practical application if it advances toward clinical use
Liposomes, owing to their lipid bilayer structure that mimics skin composition, enhance drug solubility and partitioning, facilitate deeper skin penetration, and improve therapeutic efficacy, making them ideal carriers for transdermal applications
Behavioral testing was followed by biochemical analyses on colon, faces, serum, cerebellum, and prefrontal cortex, assessing tryptophan metabolites, serotonin (5-HT) pathway intermediates, neurotransmitters (GABA, glutamate, dopamine, acetylcholine) via UPLC, UPLC-TQD, and ELISA, alongside gut microbiota profiling through 16S r RNA sequencing