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Clin Endocrinol (Oxf) 44 : 501514 Unterman TG (1993) Insulin-like growth factor binding protein-1: identification, purification, and regulation in fetal and adult life

Since antibiotics do not distinguish between beneficial or harmful organisms, antibiotics can diminish the beneficial gut flora responsible for thiamine production

Other timessuch as after prolonged heat exposure, strenuous exercise, illness, or significant dehydrationit can be difficult to replace fluids quickly enough by drinking alone