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Instead, AstraZeneca has built one of the industry's strongest oncology franchises through Tagrisso, Imfinzi, Calquence, and Lynparza, and a cardiovascular dominance through Farxiga

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The peptide itself was first identified in human plasma in the early 1970s, and the copper-bound form was recognized shortly afterward as the biologically relevant species in many of the contexts where the tripeptide's activity was characterized

Several strategies for selecting protective blood stage or transmission-blocking antigens were proposed, with some focused on functionally relevant molecules and others using pragmatic approaches like previously defined surface exposed, neutralization sensitive and conserved molecules