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Discussion As one of the most complex biological processes that occur during human life, the wound repair process involves four steps that include inflammation around the site of injury, angiogenesis and the development of granulation tissue, repair of the connective tissue and epithelium, and ultimately remodeling that leads to a healed wound.1 The clinical treatment of skin loss due to severe and massive burns or wounds continues to be a major problem in surgical procedures

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They have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease

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