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Mild side effects include nausea, stomach pain, and rash, which may occur in sensitive individuals but resolve without medical intervention

If the ECM is built too aggressively and haphazardly, you get a raised, thick, unappealing scar

DOI: 10.1038/s41467-020-14629-x Assefa B et al

The CAII enzyme is a cytoplasmic protein that, within the renal epithelial cell, forms a complex with several membrane bicarbonate transporters including AE1 (encoded by the SLC4A1 gene), NBC1 (Na + -bicarbonate cotransporter 1: encoded by the SLC4A4 gene), NBC3 (Na + -bicarbonate cotransporter 3: encoded by the SLC4A8 gene), and the SLC26A6 encoded protein, as well as with the proton antiporter, NHE1 (Na + -H + exchanger 1: encoded by the SLC9A1 gene)