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Menhem et al

In a systematic review of prospective cKD and MCTKD studies, more than 40 categories of adverse effects were identified, with gastrointestinal (constipation and vomiting), high serum lipid profiles, renal/genitourinary, and skeletal challenges being the most common (Table 3

192,193 Although the nature of the relationship is not entirely understood, it is believed that smoking causes blood vessel damage and dysfunction that leads to poor kidney blood flow and decreased kidney function