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CoQ 10 Supplementation in Specific Medical Conditions Cumulative evidence supports the association of low plasma CoQ 10 levels in several medical conditions such as diabetes mellitus, cancers, and congestive heart failure [2,51,52,53]

However, the intermittent, not continuous, administration of senolytics reduces concerns of toxicity, and effectively circumvents potential off-target effects due to continuous receptor occupancy or modulation of an enzyme or biochemical pathway

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