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The consistent strengthening of neurotransmission initiated by Dihexa and Nlel - AnglV could not be attributed to intrinsic fluctuations of neurotransmitter release or metabolic and mechanical influences (Yasumatsu, Matsuzaki et al

Patients usually present with chronic pain, decreased range of motion, and accompanying weakness

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It can be linked with: Pregnancy Lack of exercise A sudden change in diet A diet with not enough fibre Having to stay in bed for a long time Medicines such as morphine or codeine Loss of 'tone' of the bowel muscles in older people Whatever the cause, constipation can be uncomfortable