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To elucidate the potential impact of TTR amyloidosisassociated oxidative stress on GSH homeostasis, we quantified plasma PGA levels in three well-defined cohorts aged 55 years and older: asymptomatic carriers of the TTR-V30M mutation, symptomatic carriers with confirmed TTR amyloidosis (TTR-V30M patients), and healthy controls with the wild-type TTR genotype

Sirtuins are critically important cellular nutrient sensors in the nucleus and mitochondria [34,35,36]

Discoveries from our labs or moving into the clinic to help us all live better, longer

You stand for something, you stand courageously for what you believe in, or the opposite side of that is saying nothing and being a coward, Rodgers said