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All animals were housed at Animal Experiment Center of Wenzhou Medical University under the following conditions: 3 mice/ cage (30 20 15 cm, length width height), 12 h dark/light cycle, room temperature (24 1) C, ambient humidity (50 10) %, with free access to food and water

Inhibition of CYP51A1, either pharmacologically (e.g., with ketoconazole) or genetically, reduces DCP accumulation, reprograms the immune microenvironment, and suppresses MSS CRC progression

[2] How to Manage Discomfort After B12 Treatment Effective management of post-injection discomfort involves both practical self-care measures and appropriate medical follow-up

Sleep: Aim for 79 hours to support mitochondrial health and recovery