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IMPORTANT NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS FOR THE ANNUAL MEETING OF SHAREHOLDERS TO BE HELD ON AUGUST 3, 2026

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This indicates that targeting this pathway restores brown fat activity and systemic metabolic homeostasis in obesity

In addition, melatonin is capable to enhance the activity of SOD, CAT and GSH-Px to inhibit the formation of autophagosomes in oxidative stress-induced damaged goat spermatogonial stem cells or deoxynivalenol induced cell damage (Xu et al., 2023)