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While a causal relationship has not been established, patients with depression or other psychiatric conditions should be monitored for changes in mood or behavior, particularly during the initial weeks of treatment or following dose adjustments

These may include: Fatigue Brain fog Memory loss Neurological problems Heart palpitations Pale skin Muscle weakness Mood changes Appetite loss Constipation Infertility Side Effects of Vitamin B12 While the recommended daily amount of vitamin B12 for adults is 2.4 micrograms, higher doses have been found to be safe