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Description

Guanosine triphosphate cyclohydrolase (GCH1) has the ability to limit the production of tetrahydrobiopterin (BH4), which possesses lipophilic antioxidant properties [76, 154]

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Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect)

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