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it's an autoimmune condition where the body mistakenly attacks and destroys a protein called intrinsic factor

Since its discovery, DSIP has attracted research interest well beyond sleep, with studies exploring its effects on stress, pain, hormonal regulation, and withdrawal symptoms

Metformin, a drug used to treat type 2 diabetes, can also decrease absorption of B12 in the small intestine of 10 percent to 30 percent of patients

Here's where it gets interesting: some of the mechanisms tirzepatide corrects (insulin resistance, chronic inflammation, leptin excess) are the very mechanisms driving obesity-related low supply