glutathione thyroid antibodies peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in cancer Relationship between thyroid antibody levels

The results indicate a protective role of GSTP1 by enhancing GSH-conjugation, which might lead to a reduced protein modification, and suggest a second protective role by interfering with the unfolded protein response, thereby preventing apoptosis

Understanding the redox regulation may have important clinical ramifications in understanding the pathogenesis of liver diseases and developing therapeutic approaches

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