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A total of 17 motifs were discovered, and 10 of them were similar to known binding motifs, 7 of them were mismatched in Tomtom with any Eukaryotic linear motif resource (Fig

Overall, the available data support a cautious model in which mitochondria in the apical domain of PACs function as local ATP suppliers and Ca 2+ buffers that help maintain the secretory apparatus under physiological conditions, whereas mitochondrial failure in AP may indirectly destabilize the granule-rich apical region and facilitate pathological zymogen activation

S., Anand D., and Khanday F