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By using nanotechnology, this study promotes a shift toward topical delivery methods, such as immersion baths and spraying, as alternatives to traditional injections

Thus, TLR2/TLR4 activation promotes the dissociation of the inhibitor of nuclear factor kappa-B (I-B)/NF-B complex through a myeloid differentiation primary response 88-dependent (MyD88) signaling pathway, mediating the nuclear translocation of nuclear factor kappaB (NF-B) and specifically acting on the NLRP3 and IL-1B gene promoter regions

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doi: 10.1242/dmm.033316 152