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Curcuminoid-containing supplements taken on an empty stomach may cause gastritis and peptic ulcer disease (108)

35% (placebo) Cardiometabolic Improvements: Reductions in waist circumference, blood pressure, lipids, inflammatory markers Safety: Most common AE: nausea (25-33%)

Data on GLY from a previous, unpublished study conducted in cats were used to estimate the variance components for calculating the sample size for the GLY inclusion level study