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2 Science (1987) D-alanine in the frog skin peptide dermorphin is derived from L-alanine in the precursorRichter, Egger & Kreil (PMID 3659910)

Tolerability was evaluated through review or monitoring of medical history, physical examination findings, concomitant medications, vital signs, laboratory tests (hematology, serum chemistry, and urinalysis values), electrocardiography, adverse events, and serious adverse events

Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11

Translation limit Animal and cell findings may not predict human outcomes because metabolism, exposure, receptor expression, administration route, and disease context differ