Liver cirrhosis is associated with several abnormalities in the innate and adaptive components of the immune systems response to microbial challenge, leading to an acquired immunodeficiency state
The precedent has been set
In particular, an increase in lipoperoxide (LPO) levels damages the endothelial cells in the large intestine and exacerbates the symptoms of colitis, which can develop into colon cancer 3
Acknowledgements The authors research is funded by Instituto de Salud Carlos III (ISCIII)-Fondo de Investigacion Sanitaria (FIS)-Fondo Europeo de Desarrollo Regional FEDER (grants PI18/01366, PI21/00251, PI19/00588, P21/01453, PI18/01133, PI19/00815, PI22/00469, PI22/00050), European Research Area PerMed JTC2018 (KIDNEY ATTACK AC18/00064) and the RICORS programme to RICORS2040 (RD21/0005/0001), and also by Comunidad de Madrid en Biomedicina (grant P2022/BMD-7223, CIFRA_COR-CM)