It is an analog of angiotensin IV, an oligopeptide, and is orally active and crosses the blood-brain barrier
A wide range of phosphorylation site-specific antibodies were used in a qualitative and quantitative fashion as a specific assay for regulation of diverse cell signalling pathways ( Kinetworks Phospho-Site Screen 1.3 and KPSS-2.0 track 31 and 37 known phosphorylation sites, respectively in phosphoproteins with antibodies that recognise specific phosphorylated epitopes of the target proteins (Supplementary Tables S1 and S2)
doi: 10.3389/fnins.2025.1587818 Received 06 March 2025 Accepted 09 May 2025 Published 04 June 2025 Volume 19 - 2025 Edited by Stefano Marini, Independent Researcher, Termoli, Italy Reviewed by Elizabeth Anne McCullagh, Oklahoma State University, United States Hanif Ullah, Sichuan University, China Updates Copyright 2025 Fang, Zhou, Chen, Wang, Liu and Jia
These results demonstrate that the low molecular weight bioactive peptides contained in CPNS, such as Gly-Pro and Pro-Hyp, exert positive effects on skin hydration, elasticity, desquamation, and wrinkling