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It is recognized that nearly all PD cases are likely influenced by identifiable genetic factors, with specific genetic variants varying in frequency and effect size across individual cases

Gutierrez MW, van Tilburg Bernardes E, Changirwa D, McDonald B, Arrieta MC

therefore, if we know what the mechanisms involved in glial and neuronal alterations are, we must be able to identify the elements that can be used as effector elements and design drugs to control and reduced harm during the stage of relapse [14]

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