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Description

Diarrhea alone occurs most frequently with HCC as a consequence of the secretion of vasoactive intestinal polypeptide and gastrin by the tumor

It is proposed that such a disruption of BBB permeability produces a vicious circle in which incremental reductions in cerebral perfusion accelerates the neurodegenerative process thus facilitating further drops in cerebral perfusion [11,26,27]

Additional information Peer review information Nature Chemistry thanks Junjie Yao, Deju Ye and the other, anonymous, reviewer(s) for their contribution to the peer review of this work