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This recommendation is based on an evaluation of the published clinical data on dosage and toxicology related considerations

doi: 10.3390/molecules16108833 7

However, to ensure safety, it is important to purchase products that have been tested by an independent lab whenever possible

"And it's not because of any magic it's because these are natural substances that our bodies make and are familiar with, so that's what gives them this incredible safety profile." The FDA, however, has publicly stated that there is not enough evidence from human clinical trials on the safety or efficacy of these drugs