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TB-500 works through actin regulation Overlapping tissue targets: Both have been studied in connective tissue and wound healing models Theoretical synergy: Researchers hypothesize complementary effects, though combination studies are limited The combination is popular in research protocols, though published head-to-head or combination studies remain sparse

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Elevated levels of both NE and NETs are observed in tissue samples of patients with HS, and NETs from HS lesions are associated with worsening disease (71)

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