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These flavone compounds, including acacetin, baicalein, baicalin, chrysin, vitexin, scutellarein, kumatakenin, and apigenin-7-O-(6-p-coumaroyl)-glucoside, prevent and treat diseases by targeting multiple pathways to inhibit ferroptosis (ivanovi et al., 2024)

Imunotherapy in combination with chemotherapy is emerging as a new standard of care in this setting, and the approval of Imfinzi offers an important new option for patients with mismatch repair deficient disease, Dave Fredrickson, executive vice president of the oncology business unit at AstraZeneca, said in a press release