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That is one reason your clinician may ask about your full medication list, digestive history, and blood glucose patterns before considering therapy

Rare but serious risks include pancreatitis, gallbladder disease, and a thyroid C-cell tumor risk based on rodent studies (semaglutide carries a boxed warning and is contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2)

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In almost all cases, sermorelin therapy will be avoided during pregnancy and lactation to err on the side of caution, unless there are special circumstances and a consensus that treatment is necessary