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Age, family history, and the presence of the apolipoprotein E 4 allele have been found to be significant risk factors for the development of Alzheimer disease and all-cause dementia.1-3 More recently, a high plasma concentration of homocysteine has also been shown to be a risk factor for Alzheimer disease and dementia.4 Docosahexaenoic acid (DHA), an -3 polyunsaturated fatty acid found in some foods and many tissues in the body, also appears to be important in affecting the risk of dementia

Cadmium, methylmercury, mercury, and lead inhibition of calf liver glutathione S-transferase exhibiting selenium-independent glutathione peroxidase activity

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