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This can interfere with blood flow to and from the rectum (the last six inches of the large intestine) and the anus, causing blood to pool in the veins around the anus, enlarging them

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doi: 10.3389/fphar.2022.1026182 Received 23 August 2022 Accepted 23 November 2022 Published 14 December 2022 Volume 13 - 2022 Edited by Junmin Zhang, Lanzhou University, China Reviewed by Yurong Lai, Gilead, United States Mei-Hua Qu, Weifang Second Peoples Hospital, China Updates Copyright 2022 He, Feng, Guo, Zhou, Li, Zhang, Zhang, Wang, Wang, Hao, Zhang, Gao, Gu, Zhang, Li and Li

Storage & Handling Recommended storage: 28 C in a clean, dry environment, protected from direct light and moisture