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Metabolic oxidative stress elicited by the copper(II) complex [cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment

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-6 PUFA typically come from animal sources (meat, especially chicken, and eggs) and to a lesser extent from plant sources (soy, sunflower seeds and oils), while fatty fish and fish oils, leafy green vegetables, vegetable oils, nuts and seeds are rich in -3 PUFA [120]

these factors make GLP-1 RAs an alternative initial treatment option, with or without metformin based on glycemic needs, in T2DM patients with indicators of high-risk or established heart failure (HF) or CKD who cannot tolerate an SGLT2 inhibitor