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Treatment with perindopril reduces severe acute respiratory syndrome-related coronavirus 2 spike protein-induced inflammatory and oxidative stress responses in cells and significantly blunted apoptosis and ROS (130)

Chang, JY, Mehran, RJ, Feng, L, Verma, V, Liao, Z, Welsh, J, Lin, SH, O'Reilly, M, Jeter, M, Balter, PA, McRae, SE, Berry, D, Heymach, JV, Roth, JA, Antonoff, MB, Hofstetter, WL, Rajaram, R, Rice, DC, Sepesi, B, Swisher, SG , Vaporciyan, AA, Walsh, GL, DeGraaf, C, Correa, AM, Chen, A, Gandhi, S, Komaki, R, Lee, PP, Nguyen, Q, Ning, M, Gao, S, Pollard-Larkin, JM, Nitsch, PL, Sadagopan, R, Wang, X

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Also, the strong stacking of those N-doped graphite carbon in nanozymes generally induces the frustrated diffusion of bio-substrates to metal sites