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Polycystic ovary syndrome Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, insulin resistance, ovulatory dysfunction, and polycystic ovarian morphology [131], with a reported prevalence ranging from 3 to 15% of women of childbearing age [132]

They were Adolf Jarisch and Karl Herxheimer, respectively, and this phenomenon became known as a Jarisch Herxheimer reaction

Vitamin C: For each additional 1 mg per day in dietary vitamin C intake, studies showed a 6% lower risk for severe headaches and migraines