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Second, the role of metabolic reprogramming in ferroptosis highlights how sustained mechanical stress and inflammation reshape lipid, amino acid, iron, and glucose metabolic pathways in OA chondrocytes and synovial cells

In China it is used in traditional medicine and as a colorant, in Japan in tea, in Korea in drinks, in Thailand in cosmetics, and in the US as a preservative and coloring agent in food items like mustard, cheese, butter, and chips

Past that window, peptide concentration drifts downward through chemical degradation pathways

The reduced state is ready to neutralize free radicals while the oxidized glutathione performs other functions