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Metastatic CD is a rare skin manifestation of IBD that is characterized by ulcerating nodules typically present on the anterior abdominal wall, submammary area, arms, legs, or perianal region

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The stirring continued for an additional 12 h at 50 C, after which the mixture was introduced to 10 mL of deionized water while being sonicated

Rather than viewing copper simply as a free metal ion, coordination chemistry explains how binding to a peptide creates a new chemical complex with distinct structural and physicochemical properties