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While these findings remain encouraging, much of the published evidence has been generated through laboratory and animal models, and additional research is needed to further define its biological effects

Third, observational studies overstate correlationsserum EPA/DHA levels (63, 72) may be a marker of an overall healthy diet (e.g., high fish intake often coincides with high fiber and vitamin intake) rather than a direct driver of depression (62, 72)

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Some plant species have the ability to flourish in soil that is polluted with HMs and may collect substantial levels of metals in such soil (Lombi et al., 2002)