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Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y (2023) Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis

Tesamorelin + ipamorelin work through complementary GH-release mechanisms: tesamorelin activates GHRH receptors on pituitary somatotrophs, while ipamorelin selectively stimulates ghrelin receptors without cortisol or prolactin elevation