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Int J Mol Sci 21(18):6669

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The most common GABA-A receptor subunit types in the brain are 1, 2, and 2 ( GABA-B receptors (metabotropic receptors) are G-protein coupled receptors that have a negative effect on presynaptic voltage-activated Ca 2+ channels but a positive effect on postsynaptic inwardly corrected K + channels ( + channels, inactivating voltage-stalled Ca 2+ channels, and inhibiting adenylyl cyclase